Homogenizers & High-Pressure Pumps
Industries like pharmaceutical and dairy use the process of homogenization on materials like liquid drugs, pills, and milk products to ensure uniformity throughout the solution. There are several homogenization methods with the mortar and pestle being one of the oldest ways to homogenize materials.
Labs and large hygienic plants have no room for hundreds of mortars and pestles nor the funds to have them manned. Highland Equipment Inc. produces a variety of hygienic homogenizers that achieve the material disruption desired for specific applications.
What is a Hygienic Homogenizer Used For?
A homogenizer is used to mix equally two or more types of insoluble materials. It can be used to combine tissues, plants, food, soils, and much more. Different models can be found in both laboratory settings and as part of hygienic equipment.
The main goal of the homogenizer is to achieve an equal mixture of the materials using a pressurized system. Most alloys, air, and even medical-grade saline solutions are made through homogenization. Homogeneous mixtures appear even to the naked eye and are made up of a single state of matter. The process helps keep the chemical composition the same for any sample taken of the mixture.
High vs. Low-Pressure Homogenization: Which Is Better?
Materials that can be used in the process of homogenization vary widely and so the process of homogenization must vary to suit the materials being processed. High or low pressure can be used to achieve the best mixture depending on the materials used, so each homogenization method is better suited to different circumstances. Laboratories that have access to both low- and high-pressure equipment can optimize productivity.
High-quality, high-pressure homogenizers available on the market can offer some custom options. Settings can be adjusted to easily control forces in the homogeneous process like cavitation, shear, and pressure. Acquiring a high-pressure homogenizer with a low-pressure setting allows for greater use without buying separate equipment.
What are the different types of homogenizers we offer?
Highland Equipment offers a variety of homogenizers to fit the needs of your application. We offer the following types of homogenizers:
Rotor Stator Homogenizers
Rotor-Stator homogenization employs the use of centrifugal forces to thoroughly liquify softer and smaller materials. It utilizes the rotor’s rotating metal shaft within the metal casing of the stator to generate a vortex that draws in the material where the shear forces in the confined area tear apart the sample and forces the mixture out through slots in the stator.
Bead Mill Homogenizers
In bead mill homogenization, small beads collide with the samples, tubes, and other beads inside a container that is shaken or otherwise moved vigorously to unify the material. Samples can be processed with or without water and harder substances can be processed. Many models can process up to 24 samples at one time.
Ultrasonic Homogenizers (Sonicators)
The rapid vibration of the ultrasonic homogenizer wand in a solution disrupts cells through cavitation and ultrasonic waves. This process is best for solutions than for intact tissue samples. Ultrasonic homogenizers can shear DNA, create emulsions, disperse nanoparticles, and reduce the size of the particles in a solution.
Mortar & Pestle Homogenizers
The tried-and-true method of homogenization, the mortar and pestle, has been around for generations. The process is achieved by applying pressure against a solid container with a hard and blunt object. There are several types of models available including the Potter, Potter-Elvehjem, Dounce, and Tenbroeck. The equipment is durable enough to be washed and reused, or in some cases recycled. Even though it is a one-sample, low throughput process, the cost of the setup can be worth the use.
Homogenizers that use high pressure to push liquid samples through a valve or slatted membrane achieve homogenization through the high shear it produces. The liquid is pushed from the pressurized tank through the valve or membrane where the liquid will encounter high shear from the force, large pressure drop, and cavitation, which all contribute to the homogenization of the material. A high-pressure homogenizer can process very large volumes of material and can be used for emulsions and cell lysis.
Highland Equipment has the Homogenizers to fit your needs
From small liquid samples to large sample sizes, we have a homogenizer that can suit your needs and budget. Highland Equipment is ready to assist you to find the perfect fit. Contact us now for fast assistance or request a quote today!